Upon experience with previous games and with similar fundamentals when it comes to handling multiple mods you can have your own load order with little or no conflicts to each other.
I’ve gone through almost all files within Nexus to test if it’s good or will it satisfy my curiosity or need, before I used a load manager which auto-sorts everything for me which on most occasions due to the enormous amount of mods it seems to crash my game even with the auto-sort and updating unless I use my exported working load order. But all-in-all it all comes down to whether your game will experience a CTD (crash-to-desktop) or not. Most people use load order managers to handle positioning of the mods they’ve downloaded whether it be automatically sorted for them or manually done.
